International Journal of Nanomedicine (Mar 2018)
Enhanced bioactivity of GO–Fe3O4 nanocomposite against pathogenic bacterial strains
Abstract
Rajni Singh,1 Mony Sreedharan Smitha,1 Stalin Karuppiah,2 Surinder P Singh2 1Amity Institute of Microbial Biotechnology, Amity University, Noida, Uttar Pradesh, 2CSIR-National Physical Laboratory, New Delhi, Delhi, India Abstract: GO with –OH, –CHO, –CO, –COOH, and epoxide groups is considered more suitable than other commonly used materials for biomedical applications. The presence of –CO, –CHO, and –OH groups renders the easy functionalization of GO by biomolecules and drugs. Therefore, in this study, we designed a multifunctional GO–Fe3O4 nanocomposite and investigated its bactericidal activity against different bacterial strains with an evaluation of percentage inhibition. Our results revealed the potential of GO–Fe3O4 nanocomposites as an effective bactericidal, which can be used for dynamic applications in medical devices and food and other industries. Keywords: graphene oxide, GO nanocomposites, GO–Fe3O4, pathogenic strains, antibacterial