Nature Communications (Sep 2022)

A Dilp8-dependent time window ensures tissue size adjustment in Drosophila

  • D. Blanco-Obregon,
  • K. El Marzkioui,
  • F. Brutscher,
  • V. Kapoor,
  • L. Valzania,
  • D. S. Andersen,
  • J. Colombani,
  • S. Narasimha,
  • D. McCusker,
  • P. Léopold,
  • L. Boulan

DOI
https://doi.org/10.1038/s41467-022-33387-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

Read online

Mechanisms ensuring developmental precision are poorly understood. Here Blanco-Obregon et al. report reciprocal feedback between Dilp8 and Ecdysone, two hormones required during a precise time window of Drosophila development for organ size adjustment.