Progressing cerebral atherosclerosis: clinical, biochemical and morphological aspects

Abstract

In the article, basic pathogenic mechanisms of progression ofcerebral atherosclerosis leading to ischemic stroke are discussed.The ultrasound, morphological and biochemical predictorsof changes of the atherosclerotic plaque structure arepresented. A multifactorial nature of pathogenesis of progressingcerebral atherosclerosis as a key cause of ischemic strokedetermines the need for further studies of different aspects ofthis problem, from vessel and brain morphology to metabolicparameters and various blood characteristics (biochemical,lipid, conformational, and hemostatic).

Keywords

• progressing cerebral atherosclerosis
• atherosclerotic plaque
• inflammation markers
• metabolic syndrome