Cell Death and Disease (Mar 2022)
SGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition
- Xi Su,
- Dong Chen,
- Lizhang Zhu,
- Hao Jia,
- Jiaxuan Cai,
- Peng Li,
- Bin Han,
- Donglai Wang,
- Hongtao Li,
- Jiaqian Fan,
- Mengwei Gu,
- Yaqi Zhou,
- Haixia Guan,
- Wei Wei
Affiliations
- Xi Su
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Dong Chen
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Lizhang Zhu
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Hao Jia
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Jiaxuan Cai
- Center for Energy Metabolism and Reproduction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
- Peng Li
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Bin Han
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Donglai Wang
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Hongtao Li
- Department of Statistics and Data Science, Southern University of Science and Technology
- Jiaqian Fan
- School of Life and Health Sciences, Chinese University of Hong Kong
- Mengwei Gu
- Beijing Century Joyo Information Technology Co., Ltd
- Yaqi Zhou
- Department of Otorhinolaryngology, Peking University Shenzhen Hospital, ShenZhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- Haixia Guan
- Department of Endocrinology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences
- Wei Wei
- Department of Thyroid and Parathyroid Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Centre
- DOI
- https://doi.org/10.1038/s41419-022-04598-y
- Journal volume & issue
-
Vol. 13,
no. 3
pp. 1 – 9
Abstract
A schematic model of SGSM2 suppressing the progression of RASWT thyroid cancer.
