A facile synthesis and the antimicrobial activity of some 4-aryltriazoles

Abstract

Some 4-aryltriazoles were synthesized and tested for their antibacterial effects against Bacillus cereus, Pseudomonas testosteroni, Klebsiella pneumoniae Micrococcus flavus, and Citrobacter freundii. The 4-aryltriazoles were obtained by cyclization of the potassium salt of the appropriately substituted dithiocarbazinic acid with aromatic amines. The new synthesized compounds were characterized using infrared and 1H nuclear magnetic resonance spectroscopy and further supported by mass spectrometry.

Keywords

• 4-aryltriazoles
• synthesis
• antibacterial activity