Oseltamivir (Tamiflu)-induced bilateral acute angle closure glaucoma and transient myopia

Abstract

A 27-year-old woman developed bilateral acute angle closure glaucoma (AACG) and transient myopia after taking oseltamivir for four days. On the fourth day, she received systemic and topical intraocular pressure (IOP)-lowering agents, and IOP decreased in both eyes. However, her visual acuity was unchanged. A myopic shift of -5.25 D OD and -5.0 D OS was estimated to have occurred in the acute phase. A-scan ultrasonography and Pentacam showed markedly shallow anterior chambers and increased lens thickness. Ultrasound biomicroscopy revealed an annular ciliochoroidal effusion with forward displacement of the lens-iris diaphragm. Ciliochoroidal effusion and transient myopia were resolved after discontinuation of oseltamivir.

Keywords

• Malignant glaucoma
• pseudophakic
• surgical management
• zonulo-hyaloido-vitrectomy
• Automated retinal imaging
• diabetic retinopathy
• screening
• Low vision
• low vision aids
• quality of life
• Children
• congenital cataract
• hydrophobic acrylic intraocular lens
• intraocular lens implantation
• myopic shift
• polymethyl methacrylate
• Cost-effectiveness
• glaucoma
• pharmacoeconomics
• External limiting membrane
• macular hole
• predictors
• Optic nerve head drusen
• optical coherence tomography
• papilledema
• pseudopapilloedema
• Crowding
• logMAR chart
• refractive error
• screening
• visual acuity
• Acute retinal pigment epithelitis
• multifocal electroretinogram
• optical coherence tomography
• Anterior chamber
• intraocular parasite
• Linguatula serrata (tongue worm)
• subluxated lens
• vitrectomy
• Carbonic anhydrase inhibitor
• Danon disease
• ERG
• retinal disease
• SD-OCT
• Levodopa
• occlusion amblyopia
• reverse amblyopia
• Acute angle closure glaucoma
• ciliochoroidal effusion
• oseltamivir
• transient myopia