Renal Failure (Dec 2022)

Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function

  • Xiao-Pei Wang,
  • Ying Ma,
  • Jing Lv,
  • Yu Liang,
  • Li Jin,
  • Wan-Hong Lu,
  • Chang-Na Liang,
  • Bao Qian,
  • Zhao Li

DOI
https://doi.org/10.1080/0886022X.2022.2148537
Journal volume & issue
Vol. 44, no. 1
pp. 2085 – 2092

Abstract

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Introduction This cross-sectional study investigated the influence of dietary protein intake (DPI) on serum phosphate levels in peritoneal dialysis (PD) patients and determined the DPI cutoff required to prevent hyperphosphatemia.Methods A total of 504 PD patients were categorized into fast (4 h dialysate/plasma [D/P] creatinine clearance ≥0.65) or slow ( 1.0 g/kg/d (p < 0.001). High DPI only increased the hyperphosphatemia risk in slow transporters (not in high transporters). DPI ≥1.026 g increased the hyperphosphatemia risk in those patients (area under the curve: 0.66, p = 0.001).Conclusion High DPI increases the hyperphosphatemia risk in PD patients with slower peritoneal transport function.

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