Burosumab treatment in adults with X-linked hypophosphataemia: 96-week patient-reported outcomes and ambulatory function from a randomised phase 3 trial and open-label extension

• Karine Briot,
• Rachel K Crowley,
• Maria Luisa Brandi,
• Stuart H Ralston,
• Han-Wook Yoo,
• Peter Kamenický,
• Takuo Kubota,
• Nobuaki Ito,
• Martine Cohen-Solal,
• Richard Keen,
• Angela Williams,
• Muhammad K Javaid,
• Hiroyuki Tanaka,
• Robin H Lachmann,
• Karl Insogna,
• Richard Eastell,
• Yasuhiro Takeuchi,
• Anthony A Portale,
• Thomas O Carpenter,
• Hae Ii Cheong,
• Yasuo Imanishi,
• Steven Ing,
• Suzanne Jan de Beur,
• Farzana Perwad,
• Pisit Pitukcheewanont,
• Thomas J Weber,
• Annabel Nixon,
• Mark Nixon,
• Erik A Imel

Affiliations

Karine Briot

Department of Rheumatology, Hôpital Cochin, Paris, France

Rachel K Crowley

Department of Endocrinology, St Vincent’s University Hospital, Dublin, Ireland

Maria Luisa Brandi

FIRMO Foundation, Florence, Italy

Stuart H Ralston

Rheumatology and Bone Diseases Unit, Medical Research Council Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK

Han-Wook Yoo

Department of Pediatrics, Asan Medical Center Children’s Hospital, Seoul, Republic of Korea

Peter Kamenický

Endocrine Physiology and Pathophysiology, INSERM, Paris-Saclay University, Paris, France

Takuo Kubota

Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan

Nobuaki Ito

Division of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan

Martine Cohen-Solal

Department of Rheumatology, Hôpital Lariboisière, Paris, France

Richard Keen

Metabolic Bone Disease Unit, Royal National Orthopaedic Hospital NHS Trust, London, UK

Angela Williams

Health Economics and Outcomes Research Department, Kyowa Kirin International PLC, Marlow, UK

Muhammad K Javaid

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford, UK

Hiroyuki Tanaka

Department of Pediatrics, Okayama Saiseikai General Hospital, Okayama, Japan

Robin H Lachmann

Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK

Karl Insogna

Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA

Richard Eastell

Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK

Yasuhiro Takeuchi

Endocrine Center, Toranomon Hospital, Tokyo, Japan

Anthony A Portale

Department of Pediatrics, Division of Nephrology, University of California, San Francisco, California, USA

Thomas O Carpenter

Department of Pediatrics and Department of Orthopedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, USA

Hae Ii Cheong

Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea

Yasuo Imanishi

Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan

Steven Ing

Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

Suzanne Jan de Beur

Division of Endocrinology and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Farzana Perwad

Department of Pediatrics, Division of Nephrology, University of California, San Francisco, California, USA

Pisit Pitukcheewanont

Department of Pediatric Endocrinology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California, USA

Thomas J Weber

Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Annabel Nixon

Chilli Consultancy, Salisbury, UK

Mark Nixon

Chilli Consultancy, Salisbury, UK

Erik A Imel

Department of Medicine and Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA