Nature Communications (May 2019)

The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses

  • Jingxian Duan,
  • Jorge Navarro-Dorado,
  • Jill H. Clark,
  • Nicholas P. Kinnear,
  • Peter Meinke,
  • Eric C. Schirmer,
  • A. Mark Evans

DOI
https://doi.org/10.1038/s41467-019-10055-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Although calcium signals are known to be critical for many cellular processes, how signaling elicits specific functions remains unclear. In visually striking work, Duan et al. reveal that networks of cytoplasmic nanocourses orchestrate cell activity by directing site-specific calcium signals.