Case Reports in Gastroenterology (Sep 2021)

Carcinosarcoma of the Thoracic Esophagus That Presented as Focal Ulcerative Lesion

  • Akira Yoneda,
  • Takayuki Miyoshi,
  • Taiji Hida,
  • Hanako Tetsuo,
  • Shunsuke Murakami,
  • Yoichi Koga,
  • Takashi Hamada,
  • Amane Kitasato,
  • Hiroaki Takeshita,
  • Tamotsu Kuroki

DOI
https://doi.org/10.1159/000518875
Journal volume & issue
Vol. 15, no. 3
pp. 795 – 800

Abstract

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Esophageal carcinosarcoma is a rare malignant tumor composed of both carcinomatous and sarcomatous elements. We report a case of esophageal carcinosarcoma in a 56-year-old woman with dysphagia. Esophageal ulcerative tumors were detected by endoscopy and resected by thoracoscopic esophagectomy. Carcinosarcoma was confirmed by the presence of both carcinomatous and sarcomatous tumor components. On immunohistochemistry, the sarcomatous area was positive for keratin staining, while the sarcomatous area was positive for vimentin staining. The tumor reportedly had a better prognosis than SCC of the esophagus, especially in terms of survival rate. The patient’s disease was classified as ypT3N0M0, ypStage II. No definitive diagnosis was made preoperatively. We report this case along with a review of the literature.

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