Case Report: Fecal Microbiota Transplantation for the Treatment of Generalized Eczema Occurring After COVID-19 Vaccination

Abstract

Tao Huang,1,* Yongling Lv,2,* Wei Wang,1 Yunyao Chen,1 Lixin Fan,1 Zhaowei Teng,3 Xianfeng Zhou,2,4 Hexiao Shen,2 Guang Fu1 1Gastrointestinal Surgery, Wuhan Puren Hospital, Wuhan, People’s Republic of China; 2Maintainbiotech. Ltd. (Wuhan), Wuhan, People’s Republic of China; 3Central Laboratory, The Second Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of China; 4School of Life Sciences and Health Engineering, Hubei University of Technology, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hexiao Shen; Guang Fu, Email [email protected]; [email protected]: Adverse skin reactions caused by the COVID-19 vaccine have attracted considerable attention. As we all know, the development mechanism of some skin diseases is related to the gut and skin microbiome. A 78-year-old male patient who received the COVID-19 vaccine developed generalized eczema with multiple dense black patches over the body, a widespread rash, erosion, and scabs on his limbs, as well as facial edema. The patient experienced recurrent flare-ups after conventional treatment, but then recovered well without recurrence after undergoing three fecal microbial transplantation (FMT) treatments. This rare case is reported for the first time in this study. This report demonstrates the possible potential of FMT in targeting refractory skin diseases, such as eczema, as well as diseases associated with gut microbiota disturbance after vaccination.Keywords: FMT, eczema, COVID-19 vaccine

Keywords

• fmt
• eczema
• covid-19 vaccine