Annals of Noninvasive Electrocardiology (Mar 2023)

The obesity paradox in ST‐segment elevation myocardial infarction patients: A meta‐analysis

  • Si‐Han Liu,
  • Ying‐Zi Lin,
  • Shuo Han,
  • Yuan‐Zhe Jin

DOI
https://doi.org/10.1111/anec.13022
Journal volume & issue
Vol. 28, no. 2
pp. n/a – n/a

Abstract

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Abstract Objective The aim of this study was to investigate whether there was a difference in survival after initial percutaneous coronary intervention (PCI) among ST‐segment elevation myocardial infarction (STEMI) patients with different body mass index (BMI). Methods Literature retrieval was conducted on PubMed, Web of Science, Embase, CNKI, and Wanfang databases to obtain the published studies on the survival of STEMI patients with different BMI after initial PCI from the establishment of the database to 2022. All statistical analyses were performed using STATA16.0. Results Two hundred thirty‐nine studies were retrieved, and 12 studies were eventually included. Meta‐analysis showed that overweight patients [OR = 0.66, 95% CI (0.58, 0.76), p .05], short‐term mortality [OR = 1.04, 95% CI (0.89, 1.22), p > .05], and long‐term mortality [OR = 1.07, 95% CI (0.95, 1.20), p > .05] between overweight and obese patients. Conclusion This meta‐analysis confirmed an obesity paradox in STEMI patients following PCI. The obesity paradox exists in in‐hospital, short‐term, and long‐term conditions.

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