Medical Mycology Case Reports (Mar 2016)

Isavuconazole as salvage therapy for mucormycosis

  • Bianca Graves,
  • C. Orla Morrissey,
  • Andrew Wei,
  • John Coutsouvelis,
  • Samantha Ellis,
  • Alan Pham,
  • Julian Gooi,
  • Michelle Ananda-Rajah

DOI
https://doi.org/10.1016/j.mmcr.2016.03.002
Journal volume & issue
Vol. 11, no. C
pp. 36 – 39

Abstract

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Mucormycosis carries a high mortality rate with few therapeutic options available. We describe a man with pulmonary/splenic mucormycosis complicating hypoplastic myelodysplastic syndrome on a background of chronic kidney disease, who achieved a complete response with salvage isavuconazole therapy following intolerance of consecutive courses of liposomal amphotericin and posaconazole therapy.

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