Venous Tumor Thrombosis and Pulmonary Metastases in a Case of Adrenal Neuroblastoma—Occurrence of Two Rare Manifestations in a Single Patient: Case Report and Review of Literature

Abstract

Unlike other pediatric extra cranial solid neoplasms, neuroblastomas have very low incidence of pulmonary metastases. Neuroblastomas also tend to encase rather than infiltrate the major vessels with very low incidence of tumor thrombus. Even in cases with inferior vena cava tumor thrombosis, pulmonary metastases are a rare occurrence. These patients usually show widespread disseminated disease at presentation. We present a rare case of adrenal neuroblastoma with tumor thrombus and bilateral pulmonary metastases at presentation. This presentation can be confused with adrenocortical carcinoma and differentiating between the two is essential for further management.

Keywords

• neuroblastoma
• pulmonary metastases
• tumor thrombosis