Hypertrophic pulmonary osteoarthropathy secondary to pulmonary malignancy: A case report

Abstract

Background: Hypertrophic pulmonary osteoarthropathy is a rare type of paraneoplastic rheumatic manifestation which classically presents with bilateral, symmetrical periostitis of long bones, digital clubbing, and non-inflammatory arthritic pain and swelling secondary to a systemic condition, most commonly pulmonary malignancy. Case: This report presents a case of hypertrophic pulmonary osteoarthropathy which presented with orthopedic pain in the form of increasingly painful knees and bilateral periosteal reactions to the distal femur secondary to pulmonary malignancy. Conclusion: We present this case to bring awareness to the clinical and radiographic presentation of this condition in order to raise clinical suspicion and aid in future diagnosis. The authors believe that a high index of suspicion and further evaluation for underlying conditions is warranted in the setting of bilateral, symmetrical periostitis of long bones, digital clubbing, and non-inflammatory arthritic pain and swelling, as in the presented case.

Keywords

• Hypertrophic pulmonary osteoarthropathy
• Malignancy
• Periostitis
• Lower extremity
• Orthopedics