Advances in Laboratory Medicine (May 2025)

Use of artificial intelligence to assess genetic predisposition to develop critical COVID-19 disease: a comparative study of machine learning models

  • Martín Pérez Salomón,
  • Sanchez Jimenez Flora,
  • Fuentes Cantero Sandra,
  • Jímenez Barragan Marta,
  • Sanchez Mora Catalina,
  • Borreguero Leon Juan M.,
  • Teresa Arrobas Velilla,
  • Valido Morales Agustín,
  • Delgado Torralbo Juan A.,
  • León Justel Antonio

DOI
https://doi.org/10.1515/almed-2025-0073
Journal volume & issue
Vol. 6, no. 2
pp. 181 – 189

Abstract

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Early prediction of critical COVID-19 disease is crucial for an optimal clinical management. The objective of this study was to optimize predictive models for critical COVID-19 disease. Clinical data, laboratory data and genetic polymorphisms were integrated into AI models to compare the performance of different machine learning algorithms.

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