The nutritional value, heavy metal content and lipid quality of five marine fishes from, Cameroon coast were be investigated. Fish samples from Ilisha africana, Sardinella, maderensis, Cyprinus carpio, Arius parkii and Ethmalosa fimbriata were collected at, the Douala sea port, carried to the laboratory, washed with distilled water and, processed. Proximal composition, minerals, lipid quality and heavy metal analyses, were performed using AOAC standard methods. Results show that proteins (18.43%), and lipids (3.69%) contents were higher in Ilisha africana. Cyprinus carpio had the, highest ash content (4.59%). Contents of minerals and heavy metals were found as, follows: P > Mg > K > Ca > Na > Fe > Zn > Cu > Mn and Hg > Pb > Cd > As. Oils extracted from C. carpio, A. parkii and E. fimbriata were semi-siccative while those of I. africana and S. maderensis were siccative. Thus, these fish species are good sources of proteins and, minerals that can be used for managing mineral deficiencies in humans and animals.