Advanced Hepatocellular Carcinoma in Adolescence Associated with Congenital Cholestasis: A Case Description

Abstract

This case describes the clinical course and treatment of a 17-year-old male patient with advanced hepatocellular carcinoma (HCC) arising in a non-cirrhotic liver. The disease was thought to be caused by a congenital cholestatic syndrome associated with intermittent oedema in childhood, resembling the rare Aagenaes syndrome. Treatment choices in advanced HCC arising in adolescence are discussed.

Keywords

• Hepatocellular carcinoma
• Juvenile
• Adolescence
• Treatment
• Chemotherapy
• Congenital cholestasis syndrome