Dynamics of changes in the cellular composition of the focus of inflammation in secondary chronic inflammation with the introduction of mesenchymal stem cells

Abstract

The study of the dynamics of the cellular composition of the inflammatory focus showed that an increase in the level of neutrophils, basophilic and eosinophilic leukocytes occurs during the observation period with a dominance in the central parts of the inflammation focus, aeosinophilia - similarly with a prevalence in the peripheral zones. This fact indicates the transition and the beginning of the proliferation phase. The results of our studies of the cellular composition of the inflammation focus in the dynamics of secondary chronic inflammation show that the use of MSCs leads to a decrease in the chronicity of the process. This proves the possibility of using MSCs to prevent chronic inflammation.

Keywords

• secondary chronic inflammation
• focus of inflammation
• mesenchymal stem cells