ABCD: Arquivos Brasileiros de Cirurgia Digestiva (Jan 2016)

LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS

  • João Vicente Machado GROSSI,
  • Felipe Fernandes NICOLA,
  • Ivan Alberto ZEPEDA,
  • Martina BECKER,
  • Eduardo Neubarth TRINDADE,
  • Vinicius Von DIEMEN,
  • Leandro Totti CAVAZZOLA,
  • Manoel Roberto Maciel TRINDADE

DOI
https://doi.org/10.1590/0102-6720201600s10003
Journal volume & issue
Vol. 29, no. suppl 1
pp. 8 – 11

Abstract

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ABSTRACT Background: The evaluation of collagen in the abdominal wall has been increasingly studied because of the relevance on collagen in the healing process after laparotomy. Aim: To evaluate the amount of collagen in the linea alba of patients undergoing laparotomic bariatric surgery and comparing with non-obese cadavers. Methods: Were evaluated 88 samples of aponeurosis from abdominal linea alba of 44 obese patients (obesity group) and 44 non-obese cadavers (control group). The samples were collected in 2013 and 2104, and were sorted according to age (18-30, 31-45 and 46-60), gender, BMI, waist and cervical circumference, and subcutaneous tissue thickness. Material for biopsy was collected from the supraumbilical region of the linea alba for immunohistochemical analysis differentiating collagen type 1 and type 3 and the 1/3 ratio. Image-Pro Plus pixel counting software was used to measure the amount of collagen. Results: The obesity group evidenced mean age 44.11±9.90 years; 18-30 age group had three (6.8%) obese individuals; 31-45 had 22 (50%) and 46-60 had 19 (43.1%). Females were present in 81.8% (n=36); BMI (kg/m²) was 48.81±6.5; waist circumference (cm) was 136.761±13.55; subcutaneous tissue thickness (cm) 4.873±0.916. Considering age groups, gender and BMI, there were statistical differences in all tests when compared with the cadavers. Conclusion: The amount of collagen in the linea alba above the umbilical region in the morbidly obese patients was smaller than in the non-obese cadavers in the same age group.

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