Clinicopathological Outlines of Post-COVID-19 Pulmonary Fibrosis Compared with Idiopathic Pulmonary Fibrosis
Roxana-Elena Cîrjaliu,
Mariana Deacu,
Ioana Gherghișan,
Angela-Ștefania Marghescu,
Manuela Enciu,
Gabriela Izabela Băltățescu,
Antonela Anca Nicolau,
Doina-Ecaterina Tofolean,
Oana Cristina Arghir,
Ariadna-Petronela Fildan
Affiliations
Roxana-Elena Cîrjaliu
Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
Mariana Deacu
Clinical Emergency “St. Andrew” Hospital of Constanta, 900591 Constanta, Romania
Ioana Gherghișan
Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
Angela-Ștefania Marghescu
Department of Anatomopathology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Manuela Enciu
Clinical Emergency “St. Andrew” Hospital of Constanta, 900591 Constanta, Romania
Gabriela Izabela Băltățescu
Center for Research and Development of the Morphological and Genetic Studies of Malignant Pathology-CEDMOG, “Ovidius” University of Constanta, 900591 Constanta, Romania
Antonela Anca Nicolau
Center for Research and Development of the Morphological and Genetic Studies of Malignant Pathology-CEDMOG, “Ovidius” University of Constanta, 900591 Constanta, Romania
Doina-Ecaterina Tofolean
Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
Oana Cristina Arghir
Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
Ariadna-Petronela Fildan
Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
This review brings together the current knowledge regarding the risk factors and the clinical, radiologic, and histological features of both post-COVID-19 pulmonary fibrosis (PCPF) and idiopathic pulmonary fibrosis (IPF), describing the similarities and the disparities between these two diseases, using numerous databases to identify relevant articles published in English through October 2022. This review would help clinicians, pathologists, and researchers make an accurate diagnosis, which can help identify the group of patients selected for anti-fibrotic therapies and future therapeutic perspectives.
