REVERSAL OF HALOFANTRINE RESISTANCE IN PLASMODIUM FALCIPARUM BY PENFLURIDOL IN VITRO

Abstract

Penfluridol, a neuroleptic drug, considerably reversed halofantrine resistance in T9.96HF halofantrine resistant strain of Plasmodium falicparum (originally chloroquine sensitive parasites), but not in K1HF halofantrine resistant strain (originally chloroquine resistant parasites)

Keywords

• Plasmodium falicparum
• Penfluridol
• T9.96 HF
• K1 HF