Nature Communications (Feb 2016)

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

  • Bhaskar Dutta,
  • Alaleh Azhir,
  • Louis-Henri Merino,
  • Yongjian Guo,
  • Swetha Revanur,
  • Piyush B. Madhamshettiwar,
  • Ronald N. Germain,
  • Jennifer A. Smith,
  • Kaylene J. Simpson,
  • Scott E. Martin,
  • Eugen Buehler,
  • Iain D. C. Fraser

DOI
https://doi.org/10.1038/ncomms10578
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 15

Abstract

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Analysis of RNAi screens is a multi-step process requiring the sequential use of several unrelated resources. Here the authors generate an online resource integrating RNAi analytic tools and filters into a seamless workflow, which improves the specificity, selectivity and reproducibility of the results.