Nature Communications (Oct 2019)

A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells

  • Jan N. Galle,
  • Tim Fechtner,
  • Thorsten Eierhoff,
  • Winfried Römer,
  • Johannes H. Hegemann

DOI
https://doi.org/10.1038/s41467-019-12419-8
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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The Chlamydia pneumoniae adhesin LIPP plays a role in host cell entry and infection. Here, the authors find that LIPP binds to the host plasma membrane and mediates phosphatidylserine translocation, enhancing pathogen internalization without induction of apoptosis.