Current Problems in Cancer: Case Reports (Mar 2025)

Unanticipated recurrence of muscle-invasive bladder cancer: A case report

  • Farzad Allameh,
  • Afshin Moradi,
  • Azadeh Rakhshan,
  • Sina Samenezhad,
  • Amir Alinejad Khorram

Journal volume & issue
Vol. 17
p. 100357

Abstract

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Muscle-invasive bladder cancer management often involves radical cystectomy, but bladder preservation protocols have gained recognition as a low-morbidity alternative for the management of carefully selected patients. However, close follow-up is crucial for prompt diagnosis of cancer recurrence. We report a case of muscle-invasive bladder cancer managed using a bladder preservation approach. Although cystoscopy and random biopsy findings appeared unremarkable during follow-up, tumor recurrence occurred in the muscular propria without involving the bladder mucosa. This case underscores the importance of revising follow-up protocols to ensure optimal patient care.

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