Emergence of native peptide sequences in prebiotic replication networks

Jayanta Nanda; Boris Rubinov; Denis Ivnitski; Rakesh Mukherjee; Elina Shtelman; Yair Motro; Yifat Miller; Nathaniel Wagner; Rivka Cohen-Luria; Gonen Ashkenasy

doi:10.1038/s41467-017-00463-1

Nature Communications (Sep 2017)

Emergence of native peptide sequences in prebiotic replication networks

Jayanta Nanda,
Boris Rubinov,
Denis Ivnitski,
Rakesh Mukherjee,
Elina Shtelman,
Yair Motro,
Yifat Miller,
Nathaniel Wagner,
Rivka Cohen-Luria,
Gonen Ashkenasy

Affiliations

Jayanta Nanda: Department of Chemistry, Ben-Gurion University of the Negev
Boris Rubinov: Department of Chemistry, Ben-Gurion University of the Negev
Denis Ivnitski: Department of Chemistry, Ben-Gurion University of the Negev
Rakesh Mukherjee: Department of Chemistry, Ben-Gurion University of the Negev
Elina Shtelman: Department of Chemistry, Ben-Gurion University of the Negev
Yair Motro: Department of Chemistry, Ben-Gurion University of the Negev
Yifat Miller: Department of Chemistry, Ben-Gurion University of the Negev
Nathaniel Wagner: Department of Chemistry, Ben-Gurion University of the Negev
Rivka Cohen-Luria: Department of Chemistry, Ben-Gurion University of the Negev
Gonen Ashkenasy: Department of Chemistry, Ben-Gurion University of the Negev

DOI: https://doi.org/10.1038/s41467-017-00463-1
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 9

Abstract

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The synthesis of biopolymers in living cells is perfected by complex machinery, however this was not the case on early Earth. Here the authors show the role of non-enzymatic replication in the enrichment of certain products within prebiotically relevant mixtures.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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