Mathematical Biosciences and Engineering (Jan 2022)

Mathematical modeling and machine learning for public health decision-making: the case of breast cancer in Benin

  • Cyrille Agossou,
  • Mintodê Nicodème Atchadé,
  • Aliou Moussa Djibril,
  • Svetlana Vladimirovna Kurisheva

DOI
https://doi.org/10.3934/mbe.2022080
Journal volume & issue
Vol. 19, no. 2
pp. 1697 – 1720

Abstract

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Breast cancer is the most common type of cancer in women. Its mortality rate is high due to late detection and cardiotoxic effects of chemotherapy. In this work, we used the Support Vector Machine (SVM) method to classify tumors and proposed a new mathematical model of the patient dynamics of the breast cancer population. Numerical simulations were performed to study the behavior of the solutions around the equilibrium point. The findings revealed that the equilibrium point is stable regardless of the initial conditions. Moreover, this study will help public health decision-making as the results can be used to minimize the number of cardiotoxic patients and increase the number of recovered patients after chemotherapy.

Keywords