Symmetry
(Feb 2021)
Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
Michiya Kamio,
Weina Jiang,
Hiroki Osada,
Masayuki Fukuoka,
Hajime Uchida,
Ryuichi Watanabe,
Toshiyuki Suzuki,
Hiroshi Nagai
Affiliations
Michiya Kamio
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
Weina Jiang
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
Hiroki Osada
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
Masayuki Fukuoka
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
Hajime Uchida
Fisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, Japan
Ryuichi Watanabe
Fisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, Japan
Toshiyuki Suzuki
Fisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, Japan
Hiroshi Nagai
Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
DOI
https://doi.org/10.3390/sym13020361
Journal volume & issue
Vol. 13,
no. 2
Abstract
Read online
A novel symmetrical macrocyclic phthalate hexaester (1) and a known macrocyclic phthalate tetraester (2) were isolated during a natural product-exploring program on the cyanobacterium Moorea producens. Their structures were elucidated based on spectroscopic data, including nuclear magnetic resonance and high-resolution mass spectra. In the antibacterial activity test, compounds 1 and 2 showed no bioactivity at the concentrations tested.
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