Haematologica (Feb 2024)
Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia
- Lena Blumel,
- Flavia Bernardi,
- Daniel Picard,
- Jacob Torrejon Diaz,
- Vera H. Jepsen,
- Rebecca Hasselmann,
- Julian Schliehe-Diecks,
- Jasmin Bartl,
- Nan Qin,
- Beat Bornhauser,
- Sanil Bhatia,
- Blerim Marovka,
- Veronique Marsaud,
- Florent Dingli,
- Damarys Loew,
- Martin Stanulla,
- Jean-Pierre Bourqin,
- Arndt Borkhardt,
- Marc Remke,
- Olivier Ayrault,
- Ute Fischer
Affiliations
- Lena Blumel
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Flavia Bernardi
- Institut Curie, CNRS UMR, INSERM, PSL Research University, Orsay, France; CNRS UMR 3347, INSERM U1021, Universite Paris Sud, Universite Paris-Saclay, Orsay
- Daniel Picard
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Jacob Torrejon Diaz
- Institut Curie, CNRS UMR, INSERM, PSL Research University, Orsay, France; CNRS UMR 3347, INSERM U1021, Universite Paris Sud, Universite Paris-Saclay, Orsay
- Vera H. Jepsen
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Rebecca Hasselmann
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Julian Schliehe-Diecks
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Jasmin Bartl
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf, Germany; Group for Interdisciplinary Neurobiology and Immunology - INI-research, Institute of Zoology, University of Hamburg, Hamburg
- Nan Qin
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Beat Bornhauser
- Department of Oncology and Children’s Research Centre, University Children’s Hospital Zurich, Zurich
- Sanil Bhatia
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Blerim Marovka
- Department of Oncology and Children’s Research Centre, University Children’s Hospital Zurich, Zurich
- Veronique Marsaud
- Institut Curie, CNRS UMR, INSERM, PSL Research University, Orsay, France; CNRS UMR 3347, INSERM U1021, Universite Paris Sud, Universite Paris-Saclay, Orsay
- Florent Dingli
- Institut Curie, PSL Research University, Centre de Recherche, CurieCoreTech Spectrometrie de Masse Proteomique, Paris
- Damarys Loew
- Institut Curie, PSL Research University, Centre de Recherche, CurieCoreTech Spectrometrie de Masse Proteomique, Paris
- Martin Stanulla
- Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover
- Jean-Pierre Bourqin
- Department of Oncology and Children’s Research Centre, University Children’s Hospital Zurich, Zurich
- Arndt Borkhardt
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Marc Remke
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- Olivier Ayrault
- Institut Curie, CNRS UMR, INSERM, PSL Research University, Orsay, France; CNRS UMR 3347, INSERM U1021, Universite Paris Sud, Universite Paris-Saclay, Orsay
- Ute Fischer
- Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf, Medical Faculty, and University Hospital Dusseldorf, Dusseldorf, Germany; German Cancer Consortium (DKTK), partner site Essen/Dusseldorf, Dusseldorf
- DOI
- https://doi.org/10.3324/haematol.2023.283928
- Journal volume & issue
-
Vol. 999,
no. 1
Abstract
Not available.
