Multifunctional Profiling of <i>Moringa oleifera</i> Leaf Extracts for Topical Application: A Comparative Study of Different Collection Time
Anna Baldisserotto,
Riccardo Barbari,
Chiara Tupini,
Raissa Buzzi,
Elisa Durini,
Ilaria Lampronti,
Stefano Manfredini,
Erika Baldini,
Silvia Vertuani
Affiliations
Anna Baldisserotto
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Riccardo Barbari
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Chiara Tupini
Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, I-44121 Ferrara, Italy
Raissa Buzzi
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Elisa Durini
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Ilaria Lampronti
Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, I-44121 Ferrara, Italy
Stefano Manfredini
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Erika Baldini
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
Silvia Vertuani
Department of Life Sciences and Biotechnology, Section of Medicines and Health Products, University of Ferrara, Via Fossato di Mortara 17–19, I-44121 Ferrara, Italy
This research investigated plant extracts as a source of potential new actives in the nutritional, cosmetic, and pharmaceutical fields. Moringa oleifera, which is extensively known for its nutritional properties, has been investigated in this work by preparation, characterization, and evaluation of the antioxidant (FRAP, DPPH, ORAC, and PCL test), antifungal, photoprotective, and cytotoxicity profile against human melanoma Colo38 cell line of two different extracts (hydroalcoholic and methanolic) and one infusion of dry leaves collected from Paraguay in four distinct harvest times (February, March, April, and May 2017). The outcomes of this study highlight Moringa oleifera as a potential ally to counteract skin aging and oxidative stress, as indicated by the favorable antioxidant profile of the extracts and infusions of Paraguay, which was, in all cases, superior to that provided by the same plant species when collected from Senegal. Moreover, some samples were more efficient in preventing the photodegradation of UVA filter butyl methoxydibenzoylmethane (Avobenzone) compared to commercial filters, thus suggesting an interesting future role as natural additives in sunscreens.
