G3: Genes, Genomes, Genetics (Mar 2021)

Copper Availability Influences the Transcriptomic Response of <i>Candida albicans</i> to Fluconazole Stress

  • Elizabeth W Hunsaker,
  • Chen-Hsin Albert Yu,
  • Katherine J Franz

DOI
https://doi.org/10.1093/g3journal/jkab065
Journal volume & issue
Vol. 11, no. 4

Abstract

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AbstractThe ability of pathogens to maintain homeostatic levels of essential biometals is known to be important for survival and virulence in a host, which itself regulates metal availability as part of its response to infection. Given this importance of metal homeostasis, we sought to address how the availability of copper in particular impacts the response of the opportunistic fungal pathogen Candida albicansC. albicans4C. albicans