Defective BVES-mediated feedback control of cAMP in muscular dystrophy

Haiwen Li; Peipei Wang; Chen Zhang; Yuanbojiao Zuo; Yuan Zhou; Renzhi Han

doi:10.1038/s41467-023-37496-8

Nature Communications (Mar 2023)

Defective BVES-mediated feedback control of cAMP in muscular dystrophy

Haiwen Li,
Peipei Wang,
Chen Zhang,
Yuanbojiao Zuo,
Yuan Zhou,
Renzhi Han

Affiliations

Haiwen Li: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine
Peipei Wang: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine
Chen Zhang: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine
Yuanbojiao Zuo: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine
Yuan Zhou: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine
Renzhi Han: Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine

DOI: https://doi.org/10.1038/s41467-023-37496-8
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 14

Abstract

Read online

cAMP is an important second messenger involved in many aspects of biological processes. Here, Li et al. shows that blood vessel epicardial substance (BVES) is a negative regulator of cAMP signaling required for maintaining muscle mass and function.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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