Journal of Orthopaedic Translation (May 2025)
Chinese expert consensus on failure and revision after anterior cruciate ligament reconstruction
- Tianwu Chen,
- Yongtao Mao,
- Lunhao Bai,
- Xizhuang Bai,
- Qing Bi,
- Chen Chen,
- Liaobin Chen,
- Shiyi Chen,
- Wai Sin Chan,
- Guofeng Dai,
- Xuesong Dai,
- Lin Guo,
- Yang Guo,
- Yaohua He,
- Ning Hu,
- Yong Hu,
- Jingmin Huang,
- Xuan Huang,
- Xunwu Huang,
- Chang-Ming Huang,
- Xiaoxi Ji,
- Bin Li,
- Hung Maan Lee,
- Hongyun Li,
- Jian Li,
- Jin Li,
- Qi Li,
- Weiping Li,
- Kuanxin Li,
- Yanlin Li,
- Ning Liu,
- Songcen Lyu,
- Wei Lü,
- Xiaogang Ma,
- Kun Mi,
- Yansong Qi,
- Patrick Yung,
- Luning Sun,
- Jun Tao,
- Hong Wang,
- Jianquan Wang,
- Kai Wang,
- Qing Wang,
- Weiming Wang,
- Meng Wu,
- Yuli Wu,
- Yayi Xia,
- Chuan Xiang,
- Gengyan Xing,
- Honggang Xu,
- Wei Xu,
- Weidong Xu,
- Yongsheng Xu,
- Kun Yin,
- Hongbo You,
- Tengbo Yu,
- Jia-Kuo Yu,
- Hui Zhang,
- Keyuan Zhang,
- Lei Zhang,
- Weiguo Zhang,
- Wentao Zhang,
- Xintao Zhang,
- Xinghuo Zhang,
- Yadong Zhang,
- Jiapeng Zheng,
- Jiang Zheng,
- Jingbin Zhou
Affiliations
- Tianwu Chen
- Huashan Hospital Fudan University, Shanghai, China
- Yongtao Mao
- The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China
- Lunhao Bai
- Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China
- Xizhuang Bai
- The People's Hospital of Liaoning Province, Shengyang, Liaoning Province, China
- Qing Bi
- Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang Province, China
- Chen Chen
- Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Liaobin Chen
- Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China
- Shiyi Chen
- Huashan Hospital Fudan University, Shanghai, China; Corresponding author. Huashan Hospital Fudan University, Shanghai, No. 433, Huashan Road, Jingan District, Shanghai, 200020, China.
- Wai Sin Chan
- Health Bureau of Macau SAR Government, Macau, China
- Guofeng Dai
- Qilu Hospital of Shandong University, Jinan, Shandong Province, China
- Xuesong Dai
- The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
- Lin Guo
- The Southwest Hospital of Army Medical University, Chongqing, China
- Yang Guo
- The First Affiliated Hospital of Xiamen University, Xiamen, Fujian Province, China
- Yaohua He
- Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Ning Hu
- The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
- Yong Hu
- Sichuan Provincial Orthopedic Hospital, Chengdu, Sichuan Province, China
- Jingmin Huang
- Tianjin Hospital, Tianjin University, Tianjin, China
- Xuan Huang
- Changhai Hospital, Navy Medical University, Shanghai, China
- Xunwu Huang
- The Eighth Medical Center of the Chinese People's Liberation Army General Hospital, Beijing, China
- Chang-Ming Huang
- The 73 Group Army Hospital, Chenggong Hospital Affiliated to Xiamen University, Xiamen, China
- Xiaoxi Ji
- Huashan Hospital Fudan University, Shanghai, China
- Bin Li
- Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China
- Hung Maan Lee
- Hualien Tzu Chi Hospital, Hualien, Taiwan, China
- Hongyun Li
- Huashan Hospital Fudan University, Shanghai, China
- Jian Li
- West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
- Jin Li
- Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang Province, China
- Qi Li
- West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
- Weiping Li
- Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
- Kuanxin Li
- The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui Province, China
- Yanlin Li
- The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
- Ning Liu
- Zhengzhou Orthopedics Hospital, Zhengzhou, Henan Province, China
- Songcen Lyu
- The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
- Wei Lü
- The Second Hospital of Heilongjiang Province, Harbin, Heilongjiang Province, China
- Xiaogang Ma
- Tibet Autonomous Region People's Hospital, Lhasa, Tibet Autonomous Region, China
- Kun Mi
- Guangxi International Zhuang Medicine Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi Zhuang Autonomous Region, China
- Yansong Qi
- Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China
- Patrick Yung
- Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
- Luning Sun
- Jiangsu Province Hospital of Chinese Medicine, Nanjing, Jiangsu Province, China
- Jun Tao
- The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
- Hong Wang
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
- Jianquan Wang
- Peking University Third Hospital, Beijing, China
- Kai Wang
- Qinghai Provincial People's Hospital, Xining, Qinghai Province, China
- Qing Wang
- Jiangsu Province Hospital, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, China
- Weiming Wang
- Xinhua Hospital Affiliated to Dalian University, Dalian, Liaoning Province, China
- Meng Wu
- Lanzhou University Second Hospital, Lanzhou, Gansu Province, China
- Yuli Wu
- Changzheng Hospital, Naval Medical University, Shanghai, China
- Yayi Xia
- Lanzhou University Second Hospital, Lanzhou, Gansu Province, China
- Chuan Xiang
- The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China
- Gengyan Xing
- The Third Medical Center of the General Hospital of the People's Liberation Army, Beijing, China
- Honggang Xu
- The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China
- Wei Xu
- The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China
- Weidong Xu
- Changhai Hospital, Navy Medical University, Shanghai, China
- Yongsheng Xu
- Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China
- Kun Yin
- The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China
- Hongbo You
- Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
- Tengbo Yu
- Qingdao Municipal Hospital, University of Health and Rehabilitation Sciences, Qingdao, China
- Jia-Kuo Yu
- Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China
- Hui Zhang
- Beijing Jishuitan Hospital, Capital Medical University, China
- Keyuan Zhang
- The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China
- Lei Zhang
- Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China
- Weiguo Zhang
- The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China
- Wentao Zhang
- The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong Province, China
- Xintao Zhang
- Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China
- Xinghuo Zhang
- Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing, China
- Yadong Zhang
- The Chinese People's Liberation Army General Hospital, Beijing, China
- Jiapeng Zheng
- Southeast Hospital Affiliated to Xiamen University, Zhangzhou, Fujian Province, China
- Jiang Zheng
- Xi'an Honghui Hospital, Xi'an, Shannxi Province, China
- Jingbin Zhou
- Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
- Journal volume & issue
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Vol. 52
pp. 451 – 463
Abstract
Background: With the recent rise in anterior cruciate ligament (ACL) reconstruction surgeries in China, a corresponding increase in surgical failures has been observed. Variability in primary surgical techniques and the intricacies of failure mechanisms have introduced significant challenges in diagnosing failures, planning procedures, and conducting revision surgeries. Methods: In response to these challenges, the Chinese Association of Orthopaedic Surgeons (CAOS) and the Chinese Society of Sports Medicine (CSSM) initiated the development of an expert consensus on ACL reconstruction failure and revision. Utilizing a modified Delphi method, 67 domestic experts from relevant fields were invited for consensus formulation and review. Results: The expert panel achieved a high degree of consensus on twelve key aspects. The consensus clearly defines ACL reconstruction failure and outlines multiple contributing factors, with surgical errors, especially incorrect bone tunnel placement, identified as primary causes. It also emphasizes the significant impact of patient-specific variables on the likelihood of failure. Recommendations for revision surgeries include careful determination of revision indications, preserving meniscal integrity to reduce the risk of joint degeneration, and a preference for single-stage or two-stage surgeries based on individual patient evaluations. A unified approach for managing bone defects remains absent, necessitating comprehensive assessments. Graft selection should be tailored to each patient, with autografts, allografts, or synthetic ligaments as viable options. For patients with a highly positive pivot shift test or those engaged in high-demand athletic activities, anterolateral structure augmentation or reconstruction is recommended. Conclusion: The consensus emphasizes the critical need for individualized approaches in ACL revision surgery. By clearly defining failure criteria and outlining strategies for surgical revisions, these statements are expected to serve as a guide for refining clinical practice, reducing complications, and improving surgical outcomes. The translational potential of this article: 1) Establishment of Evidence-Based Clinical Guidelines: This article presents a rigorously developed expert consensus on ACL reconstruction failure and revision, providing evidence-based clinical guidelines that are directly applicable in surgical practice. The standardization of these protocols across medical institutions has the potential to reduce variability in patient care and improve surgical outcomes on a national scale. 2) Advancement of Precision Medicine in ACL Surgery: By emphasizing the need for patient-specific approaches in the management of ACL reconstruction failure, this consensus supports the advancement of precision medicine in orthopaedic surgery. The tailored recommendations for graft selection, surgical techniques, and rehabilitation protocols can lead to more personalized and effective treatments, reducing the risk of complications and enhancing recovery. 3) Catalyst for Innovation in Surgical Techniques: The article identifies critical gaps and challenges in current ACL revision practices, providing a foundation for future research and innovation. By outlining the complexities and controversies in surgical decision-making, this work serves as a catalyst for the development of new surgical techniques and technologies aimed at improving patient outcomes. 4) Framework for Future Research and Development: The consensus not only addresses immediate clinical needs but also sets a clear agenda for future research in ACL revision. By offering a structured approach to the diagnosis and management of ACL failures, this article guides both basic and translational research efforts, ensuring that future innovations are aligned with clinical realities and patient needs.