Epidemiological Cut-Off Values and Multidrug Resistance of <i>Escherichia coli</i> Isolated from Domesticated Poultry and Pigs Reared in Mwanza, Tanzania: A Cross-Section Study
Conjester I. Mtemisika,
Helmut Nyawale,
Ronald J. Benju,
Joseph M. Genchwere,
Vitus Silago,
Martha F. Mushi,
Joseph Mwanga,
Eveline Konje,
Mariam M. Mirambo,
Stephen E. Mshana
Affiliations
Conjester I. Mtemisika
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Helmut Nyawale
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Ronald J. Benju
Tanzania Veterinary Laboratory Agency, Ministry of Livestock and Fisheries, Mwanza P.O. Box 129, Tanzania
Joseph M. Genchwere
Tanzania Veterinary Laboratory Agency, Ministry of Livestock and Fisheries, Mwanza P.O. Box 129, Tanzania
Vitus Silago
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Martha F. Mushi
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Joseph Mwanga
Department of Epidemiology, Biostatistics and Behavioral Sciences, School of Public Health, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Eveline Konje
Department of Epidemiology, Biostatistics and Behavioral Sciences, School of Public Health, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Mariam M. Mirambo
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Stephen E. Mshana
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania
Increasing antimicrobial resistance (AMR) colonizing domesticated animals is a global concern threatening food safety. This study aimed at determining the prevalence of multidrug resistance (MDR) and epidemiological cut-off values (ECVs) of E. coli isolated from poultry and pigs in Mwanza, Tanzania. This cross-sectional study was conducted between June and August 2021, involving 297 pigs, 191 broilers, and 203 layers. Rectal and cloacal swabs were collected and processed following standard guidelines. ECVs were determined using normalized resistance interpretation (NRI), a computer software, and descriptive analysis was performed using STATA version 13.0. The overall prevalence of MDR E.coli was 63.2%, whereas poultry (87.5% layers and 86.3% broilers) were more colonized than pigs (31.8%) (p E. coli from broilers, layers, and pigs exhibited different resistance patterns hence different populations. Exotic breed (p p E. coli. Veterinary officers should implement regulations that prohibit the inappropriate use of antimicrobial agents in livestock keeping.
