Relationship between Peripheral Blood Eosinophil Count and Neutrophil/Lymphocyte Ratio with Number of Attacks Leading to Hospital Admission in Chronic Obstructive Pulmonary Disease

Abstract

Background & Aims: Chronic obstructive pulmonary disease is an important common respiratory disorder. Determination of the prognostic factors is important to improve the outcomes and decrease the burden of problem. We aimed to determine the relationship between peripheral blood eosinophil count and neutrophil/lymphocyte ratio (NLR) with number of attacks leading to hospital admission in patients with chronic obstructive pulmonary disease. Materials & Methods: In this cohort study, 200 consecutive patients with chronic obstructive pulmonary disease from 2016 to 2018 were enrolled including those with and without attacks leading to hospital admission and eosinophil and NLR were compared in them. Results: The results in this study demonstrated that mean eosinophil was 1.5 and 1.4 in those without and with attack without significant difference (p=0.641). The mean NLR was 4.6 and 5.9 in those without and with attack with significant difference (p=0.022). Conclusion: Totally, according to the obtained results, it is concluded that higher NLR is related to further attacks leading to hospital admissions but the eosinophil count has no significant effect in this area.

Keywords

• eosinophil
• nlr
• copd
• exacerbation