Xin yixue (Jan 2023)

Research porogress on the role of interleukin-17 in the occurrence and development of ovarian cancer

  • Wang Yuehua, Liu Juan, Liu Jie, Li Jiarong, Liu Hui, Guo Na

DOI
https://doi.org/10.3969/j.issn.0253-9802.2023.01.010
Journal volume & issue
Vol. 54, no. 1
pp. 46 – 49

Abstract

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As an important inflammatory cytokine， interleukin-17 （IL-17） plays a critical immune role in anti-infection and autoimmune diseases. Besides， IL-17 has been confirmed to play a pivotal role in the occurrence and progression of multiple malignant tumors. In recent years， the global mortality rate of ovarian cancer has been decreased， but there is a trend of younger women being diagnosed. According to the correlation studies between IL-17 and ovarian cancer， it can be predicted that IL-17 can serve as a critical biomarker in the detection， treatment and follow-up of ovarian cancer. Nevertheless， large sample size studies are urgently required. Currently， clinical trials related to the role of IL-17 in the immune therapy for multiple tumors are being undertaken. In this article， recent studies related to the role of IL-17 in ovarian cancer were reviewed， which might provide novel ideas for early detection， treatment and postoperative follow-up of ovarian cancer.

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