Halogenation of tyrosine perturbs large-scale protein self-organization

Huan Sun; Haiyang Jia; Olivia Kendall; Jovan Dragelj; Vladimir Kubyshkin; Tobias Baumann; Maria-Andrea Mroginski; Petra Schwille; Nediljko Budisa

doi:10.1038/s41467-022-32535-2

Nature Communications (Aug 2022)

Halogenation of tyrosine perturbs large-scale protein self-organization

Huan Sun,
Haiyang Jia,
Olivia Kendall,
Jovan Dragelj,
Vladimir Kubyshkin,
Tobias Baumann,
Maria-Andrea Mroginski,
Petra Schwille,
Nediljko Budisa

Affiliations

Huan Sun: School of Chemistry and Chemical Engineering, Beijing Institute of Technology
Haiyang Jia: School of Chemistry and Chemical Engineering, Beijing Institute of Technology
Olivia Kendall: Technical University of Berlin
Jovan Dragelj: Technical University of Berlin
Vladimir Kubyshkin: University of Manitoba
Tobias Baumann: Technical University of Berlin
Maria-Andrea Mroginski: Technical University of Berlin
Petra Schwille: Max Planck Institute of Biochemistry
Nediljko Budisa: Technical University of Berlin

DOI: https://doi.org/10.1038/s41467-022-32535-2
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 13

Abstract

Read online

Sun et al. has studied the genetically encodable halotyrosines in proteins of the prokaryotic cell division machinery to elucidate the general role of halogenation in cellular lifespan and oxidative damage-induced diseases such as aging and cancer.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal