Case Reports in Medicine (Jan 2010)

Sclerosing Variant of the Bronchioloalveolar Carcinoma: Imaging Findings in an Atypical Case

  • Carolina Lamas Constantino,
  • Edson Marchiori,
  • Gláucia Zanetti,
  • Antonio Muccillo,
  • Mariana Leite Pereira,
  • Guilherme Abdalla,
  • Pedro Martins,
  • Nina Ventura,
  • Rodrigo Canellas,
  • Viviane Brandão,
  • Romulo Varella de Oliveira

DOI
https://doi.org/10.1155/2010/361265
Journal volume & issue
Vol. 2010

Abstract

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Bronchioloalveolar carcinoma remains one of the most enigmatic lung cancers, demonstrating varied growth patterns, mixed histological features, and confusing clinical manifestations. This paper reports a case of an unusual form of presentation: a sclerosing type associated with desmoplastic reaction and cicatrization. A 75-year-old woman was admitted with persistent dry cough and progressive dyspnea. Physical examination showed bilateral inspiratory crackles. A chest radiograph and high-resolution computed tomography demonstrated confluent airspace nodules, forming areas of consolidation in both lungs, with signs of architectural distortion. The lung biopsy revealed a nonmucinous sclerosing bronchioloalveolar carcinoma.