Rapid electrochemical detection of coronavirus SARS-CoV-2

Thanyarat Chaibun; Jiratchaya Puenpa; Tatchanun Ngamdee; Nimaradee Boonapatcharoen; Pornpat Athamanolap; Anthony Peter O’Mullane; Sompong Vongpunsawad; Yong Poovorawan; Su Yin Lee; Benchaporn Lertanantawong

doi:10.1038/s41467-021-21121-7

Nature Communications (Feb 2021)

Rapid electrochemical detection of coronavirus SARS-CoV-2

Thanyarat Chaibun,
Jiratchaya Puenpa,
Tatchanun Ngamdee,
Nimaradee Boonapatcharoen,
Pornpat Athamanolap,
Anthony Peter O’Mullane,
Sompong Vongpunsawad,
Yong Poovorawan,
Su Yin Lee,
Benchaporn Lertanantawong

Affiliations

Thanyarat Chaibun: Biosensors Laboratory, Department of Biomedical Engineering, Faculty of Engineering, Mahidol University
Jiratchaya Puenpa: Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University
Tatchanun Ngamdee: Department of Biotechnology, School of Bioresources and Technology, King Mongkut’s University of Technology Thonburi
Nimaradee Boonapatcharoen: Pilot Plant Development and Training Institute (PDTI), King Mongkut’s University of Technology Thonburi
Pornpat Athamanolap: Biosensors Laboratory, Department of Biomedical Engineering, Faculty of Engineering, Mahidol University
Anthony Peter O’Mullane: School of Chemistry and Physics, Queensland University of Technology (QUT)
Sompong Vongpunsawad: Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University
Yong Poovorawan: Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University
Su Yin Lee: Faculty of Applied Sciences, AIMST University
Benchaporn Lertanantawong: Biosensors Laboratory, Department of Biomedical Engineering, Faculty of Engineering, Mahidol University

DOI: https://doi.org/10.1038/s41467-021-21121-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 10

Abstract

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Currently the most common method of COVID-19 diagnosis is by qRT-PCR which is slow and requires expensive instrumentation. Here the authors report an electrochemical biosensor based on isothermal rolling circle amplification for rapid detection of SARS-CoV-2 in clinical samples.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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