Journal of Lipid Research (Apr 1964)

A method for rapid microsynthesis of radioactive cholesterol esters

  • Karoly G. Pinter,
  • James G. Hamilton,
  • James E. Muldrey

Journal volume & issue
Vol. 5, no. 2
pp. 273 – 274

Abstract

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A simple method for synthesizing esters of labeled cholesterol of high specific activity is described. The formation of acyl chlorides takes 10 min and they are reacted with labeled cholesterol to form the cholesterol esters in another 5 min. Yields were 30–70% and radiopurities of 90–99.5% were achieved.