Memorias do Instituto Oswaldo Cruz (Nov 2012)

The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients

  • Renata Fragelli Fonseca,
  • Marcia Tie Kawamura,
  • José Antônio Oliveira,
  • Anselmo Teixeira,
  • Gilda Alves,
  • Maria da Glória da Costa Carvalho

DOI
https://doi.org/10.1590/S0074-02762012000700020
Journal volume & issue
Vol. 107, no. 7
pp. 953 – 954

Abstract

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Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.

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