COVID-19 infection triggered idiopathic capillary leak syndrome treated with ECMELLA
Michael Wester,
Thomas Drasch,
Roland Schneckenpointner,
Maik Foltan,
Alois Philipp,
Thomas Müller,
Bernhard Banas,
Lars S. Maier,
P.D. Matthias Lubnow
Affiliations
Michael Wester
University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany; Corresponding author. University Medical Center Regensburg, Department of Internal Medicine II, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Thomas Drasch
Department of Nephrology, University Hospital of Regensburg, Regensburg, Germany
Roland Schneckenpointner
University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany
Maik Foltan
Department of Cardiothoracic Surgery, University Hospital of Regensburg, Regensburg, Germany
Alois Philipp
Department of Cardiothoracic Surgery, University Hospital of Regensburg, Regensburg, Germany
Thomas Müller
University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany
Bernhard Banas
Department of Nephrology, University Hospital of Regensburg, Regensburg, Germany
Lars S. Maier
University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany
P.D. Matthias Lubnow
University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany
Background: Idiopathic systemic capillary leak syndrome (ISCLS) is characterized by recurrent systemic capillary leakage and hypovolemic shock. Case presentation: We report a 59-year-old Caucasian man with ISCLS and persistent hypovolemic and cardiogenic shock after COVID-19 infection. Mechanical circulatory support was provided with veno-arterial extracorporeal membrane oxygenation and a microaxial pump. Massive fluid resuscitation was needed. Subsequent complications prolonged the intensive care treatment. Mechanical circulatory support was needed for 22 days. Cardiac function eventually fully recovered, and the patient survived without neurologic compromise. Conclusions: This case of severe ISCLS triggered by COVID-19 highlights that even the most severe hypovolemic and cardiogenic shock may be reversible in ISCLS.