Medicina (May 2024)

The Association between Cafestol and Cardiovascular Diseases: A Comprehensive Review

  • Wen-Rui Hao,
  • Chun-Yao Cheng,
  • Huan-Yuan Chen,
  • Jin-Jer Chen,
  • Tzu-Hurng Cheng,
  • Ju-Chi Liu

DOI
https://doi.org/10.3390/medicina60060867
Journal volume & issue
Vol. 60, no. 6
p. 867

Abstract

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Cafestol, a bioactive compound found in coffee, has attracted considerable attention due to its potential impact on cardiovascular health. This review aims to comprehensively explore the association between cafestol and cardiovascular diseases. We delve into the mechanisms through which cafestol influences lipid metabolism, inflammation, and endothelial function, all of which are pivotal in cardiovascular pathophysiology. Moreover, we meticulously analyze epidemiological studies and clinical trials to elucidate the relationship between cafestol and cardiovascular outcomes. Through a critical examination of existing literature, we aim to provide insights into the potential benefits and risks associated with cafestol concerning cardiovascular health.

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