Rebound Hyperkalemia in Patients with Thyrotoxic Periodic Paralysis: Three Cases Reports and Literature Review

Abstract

Thyrotoxic periodic paralysis (TPP) is an endocrine emergency caused by thyrotoxicosis, mainly manifesting as periodic muscle weakness and hypokalemia, which seriously threatens the health of patients. The level of hypokalemia is closely related to the severity of muscle weakness in patients with TPP, and potassium supplementation can quickly alleviate the symptom of muscle weakness and hypokalemia. However, excessive potassium supplementation can lead to acute rebound hyperkalemia in patients with TPP, which also threatens the health of patients. This article reported 3 cases of TPP patients with acute rebound hyperkalemia caused by excessive potassium supplementation, and analyzed the risk factors for rebound hyperkalemia, in order to provide more information for the clinical treatment of TPP patients.

Keywords

• thyrotoxic periodic paralysis|paralysis, hyperkalemic periodic|hypokalemic periodic paralysis|hypokalemia|rebound hyperkalemia|case reports