Isolation and evaluation of the antioxidant actity of phenolic constituents of the Garcinia sizygiifolia

Abstract

A known compound 2,4-dihydroxyphenylethanone was isolated from the ethyl acetate extract of stem bark Garcinia sizygiifolia. The extraction was done by maseration, separation and purification were done by chromatography method .The structures of these compound was established using UV, IR, 1H and 13C NMR, HMQC and HMBC spectroscopy. The antioxidant activity of the isolated compound was tested by DPPH method. The isolated compound was a yellow solids with melting point 148-149oC. The compound exhibited antioxidant activity with IC50 96 µg/mL against DPPH

Keywords

• Antioxidant
• Phenolic
• Garcinia sizygiifolia
• dihydroxyphenylethanone