Research progress in biodegradable Zn-based materials for orthopedic applications

SUN Jiang; SHI Zhangzhi; LI Yageng; LI Xiangmin; LI Weishi; WANG Luning

doi:10.11868/j.issn.1001-4381.2021.001169

Cailiao gongcheng (Nov 2022)

Research progress in biodegradable Zn-based materials for orthopedic applications

SUN Jiang,
SHI Zhangzhi,
LI Yageng,
LI Xiangmin,
LI Weishi,
WANG Luning

Affiliations

SUN Jiang: Department of Orthopedic, Peking University Third Hospital, Beijing 100191, China
SHI Zhangzhi: Beijing Advanced Innovation Center for Materials Genome Engineering, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China
LI Yageng: Beijing Advanced Innovation Center for Materials Genome Engineering, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China
LI Xiangmin: Beijing Advanced Innovation Center for Materials Genome Engineering, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China
LI Weishi: Department of Orthopedic, Peking University Third Hospital, Beijing 100191, China
WANG Luning: Beijing Advanced Innovation Center for Materials Genome Engineering, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China

DOI: https://doi.org/10.11868/j.issn.1001-4381.2021.001169
Journal volume & issue: Vol. 50, no. 11
pp. 14 – 25

Abstract

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In recent years, zinc alloys have shown great potential as orthopedic plant materials because of their excellent biocompatibility, osteoinductive and biodegradation activities in vivo. The physiological function, degradation rate and mechanical properties of pure zinc were introduced in this review. Taking the gap between the above indicators and the clinical needs of orthopedics as the clue and the alloy elements as the classification basis, the existing achievements of researchers to improve the properties of zinc-based materials by changing the microstructure of materials and triggering the corresponding strengthening mechanism, and using the physiological synergistic function of added elements were expounded in this paper. The standard formulation, alloy design improvement and the introduction of new technologies such as additive manufacturing in the field of medical zinc based materials were discussed in order to meet the diversified needs of clinical diagnosis and treatment.

Published in Cailiao gongcheng

ISSN: 1001-4381 (Print)
Publisher: Journal of Materials Engineering
Country of publisher: China
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: http://jme.biam.ac.cn/CN/1001-4381/home.shtml

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