Developing Insights Regarding Tricuspid Valve Regurgitation: Morphology, Assessment of Severity, and the Need for a Novel Grading Scheme

Cristiane Carvalho Singulane, MD, MSc; Amita Singh, MD, FACC, FASE; Karima Addetia, MD, FACC, FASE; Megan Yamat, ACS, RDCS; Roberto Miguel Lang, MD, FASE, FACC

doi:10.1016/j.shj.2022.100026

Structural Heart (Apr 2022)

Developing Insights Regarding Tricuspid Valve Regurgitation: Morphology, Assessment of Severity, and the Need for a Novel Grading Scheme

Cristiane Carvalho Singulane, MD, MSc,
Amita Singh, MD, FACC, FASE,
Karima Addetia, MD, FACC, FASE,
Megan Yamat, ACS, RDCS,
Roberto Miguel Lang, MD, FASE, FACC

Affiliations

Cristiane Carvalho Singulane, MD, MSc: Noninvasive Cardiac Imaging Laboratories, Section of Cardiology, Heart & Vascular Center, The University of Chicago Medicine, Chicago, Illinois, USA
Amita Singh, MD, FACC, FASE: Noninvasive Cardiac Imaging Laboratories, Section of Cardiology, Heart & Vascular Center, The University of Chicago Medicine, Chicago, Illinois, USA
Karima Addetia, MD, FACC, FASE: Noninvasive Cardiac Imaging Laboratories, Section of Cardiology, Heart & Vascular Center, The University of Chicago Medicine, Chicago, Illinois, USA
Megan Yamat, ACS, RDCS: Noninvasive Cardiac Imaging Laboratories, Section of Cardiology, Heart & Vascular Center, The University of Chicago Medicine, Chicago, Illinois, USA
Roberto Miguel Lang, MD, FASE, FACC: Address correspondence to: Roberto Miguel Lang, MD, FASE, FACC, The University of Chicago Medicine, 5758 S. Maryland Avenue, MR 9067, DCAM 5509, Chicago, IL 6063; Noninvasive Cardiac Imaging Laboratories, Section of Cardiology, Heart & Vascular Center, The University of Chicago Medicine, Chicago, Illinois, USA

DOI: https://doi.org/10.1016/j.shj.2022.100026
Journal volume & issue: Vol. 6, no. 1
p. 100026

Abstract

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Current understanding that progressive tricuspid regurgitation (TR) is associated with worse outcomes has highlighted the clinical need for a more accurate assessment of TR morphology and severity. This need has been further emphasized owing to the development of a myriad of percutaneous right-sided interventions, which may offer successful treatment of TR in selected patients. Understanding the etiology and quantification of the severity of TR has important implications in the selection of novel therapeutic strategies, i.e., medical vs. percutaneous vs. surgical approaches. Newer grading schemas that better reflect the TR lesion severity have been recently proposed and may facilitate monitoring of the evolution of TR following percutaneous and/or surgical treatment. In this review, we summarize contemporary concepts regarding tricuspid valve morphology, TR etiology, and associated mechanisms and echocardiographic approaches to grade TR severity.

Published in Structural Heart

ISSN: 2474-8706 (Print); 2474-8714 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.sciencedirect.com/journal/structural-heart

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Abstract

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