Akt/mTOR integrate energy metabolism with Wnt signal to influence wound epithelium growth in Gekko Japonicus

Qinghua Wang; Zuming Mao; Zhuang Liu; Man Xu; Shuai Huang; Yin Wang; Yanran Xu; Longju Qi; Mei Liu; Yan Liu

doi:10.1038/s42003-022-04004-5

Communications Biology (Sep 2022)

Akt/mTOR integrate energy metabolism with Wnt signal to influence wound epithelium growth in Gekko Japonicus

Qinghua Wang,
Zuming Mao,
Zhuang Liu,
Man Xu,
Shuai Huang,
Yin Wang,
Yanran Xu,
Longju Qi,
Mei Liu,
Yan Liu

Affiliations

Qinghua Wang: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Zuming Mao: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Zhuang Liu: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Man Xu: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Shuai Huang: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Yin Wang: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Yanran Xu: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Longju Qi: Affiliated Nantong Hospital 3 of Nantong University, Nantong University
Mei Liu: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University
Yan Liu: Key Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University

DOI: https://doi.org/10.1038/s42003-022-04004-5
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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Low temperature inhibits the regeneration of amputated tails of Gekko japonicus by influencing the energy sensory Akt/mTOR pathway, which is also modulated by injury-induced Wnt signal.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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