A shared genetic contribution to breast cancer and schizophrenia

Donghao Lu; Jie Song; Yi Lu; Katja Fall; Xu Chen; Fang Fang; Mikael Landén; Christina M. Hultman; Kamila Czene; Patrick Sullivan; Rulla M. Tamimi; Unnur A. Valdimarsdóttir

doi:10.1038/s41467-020-18492-8

Nature Communications (Sep 2020)

A shared genetic contribution to breast cancer and schizophrenia

Donghao Lu,
Jie Song,
Yi Lu,
Katja Fall,
Xu Chen,
Fang Fang,
Mikael Landén,
Christina M. Hultman,
Kamila Czene,
Patrick Sullivan,
Rulla M. Tamimi,
Unnur A. Valdimarsdóttir

Affiliations

Donghao Lu: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Jie Song: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Yi Lu: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Katja Fall: Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University
Xu Chen: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Fang Fang: Unit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet
Mikael Landén: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Christina M. Hultman: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Kamila Czene: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Patrick Sullivan: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
Rulla M. Tamimi: Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School
Unnur A. Valdimarsdóttir: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet

DOI: https://doi.org/10.1038/s41467-020-18492-8
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

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Schizophrenia has been associated with increased risk of breast cancer, yet the risk of schizophrenia following breast cancer is unclear. Here, the authors show a bidirectional association between breast cancer and schizophrenia in Sweden and a shared genetic contribution to both diseases.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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