The effect of chondroitin sodium sulfate on oxidation-antioxidant balance in the blood serum of carrageenan-induced inflammation in the rat hindpaw

Abstract

The significant violation of pro-/antioxidative balance in serum of сarrageenan-induced inflammation in the rat paw was established. It was associated with increased levels of hydrogen peroxide and lipid peroxidation products, as well as with elevated catalase and decreased superoxide dismutase activity. All above mentioned indices was closer to control values in animals treated simultaneously with сarrageenan and drug "Drastop".

Keywords

• сarrageenan-induced inflammation, chondroprotector, serum, oxidative-antioxidant balance